Thailand

Advancing representation learning in specialized fields like medicine remains challenging due to the scarcity of expert annotations for text and images. To tackle this issue, we present a novel two-stage framework designed to extract high-quality factual statements from free-text radiology reports in order to improve the representations of text encoders and, consequently, their performance on various downstream tasks.
In the first stage, we propose a \textit{Fact Extractor} that leverages large language models (LLMs) to identify factual statements from well-curated domain-specific datasets. In the second stage, we introduce a \textit{Fact Encoder} (CXRFE) based on a BERT model fine-tuned with objective functions designed to improve its representations using the extracted factual data. Our framework also includes a new embedding-based metric (CXRFEScore) for evaluating chest X-ray text generation systems, leveraging both stages of our approach. Extensive evaluations show that our fact extractor and encoder outperform current state-of-the-art methods in tasks such as sentence ranking, natural language inference, and label extraction from radiology reports. Additionally, our metric proves to be more robust and effective than existing metrics commonly used in the radiology report generation literature. The code of this project is available at \url{https://github.com/PabloMessina/CXR-Fact-Encoder}.

ACL 2024

Extracting and Encoding: Leveraging Large Language Models and Medical Knowledge to Enhance Radiological Text Representation

chest x-ray radiology reports

text embeddings

evaluation metrics

large language models

### Welcome!
The 62nd Annual Meeting of the Association for Computational Linguistics (ACL 2024) will take place in Bangkok, Thailand from August 11th to 16th, 2024. Our Virtual Poster Sessions will take place online Thursday, August 22, 2024.

You are required to register for this event. **Please register [here](https://2024.aclweb.org/registration). **

If you have already registered, please check your inbox for an email from Underline granting you access to ACL 2024 content.

Please register!

The 62nd Annual Meeting of the Association for Computational Linguistics (ACL 2024) will take place in Bangkok, Thailand from August 11th to 16th, 2024. More information will be announced soon.

poster

People tend to use language to mention surprising properties of events: for example, when a banana is blue, we are more likely to mention color than when it is yellow. This fact is taken to suggest that yellowness is somehow a typical feature of bananas, and blueness is exceptional. Similar to how a yellow color is typical of bananas, there may also be genders that are typical of occupations. In this work, we explore this question using information theoretic techniques coupled with corpus statistic analysis. In two distinct large corpora, we do not find strong evidence that occupations and gender display the same patterns of mentioning as do bananas and color. Instead, we find that gender mentioning is correlated with femaleness of occupation in particular, suggesting perhaps that woman-dominated occupations are seen as somehow ``more gendered'' than male-dominated ones, and thereby they encourage more gender mentioning overall.

Are Female Carpenters like Blue Bananas? A Corpus Investigation of Occupation Gender Typicality

Retrieval-augmented generation (RAG) is a powerful technique to facilitate language model generation with proprietary and private data, where data privacy is a pivotal concern. Whereas extensive research has demonstrated the privacy risks of large language models (LLMs), the RAG technique could potentially reshape the inherent behaviors of LLM generation, posing new privacy issues that are currently under-explored. To this end, we conduct extensive empirical studies with novel attack methods, which demonstrate the vulnerability of RAG systems on leaking the private retrieval database. Despite the new risks brought by RAG on the retrieval data, we further discover that RAG can be used to mitigate the old risks, i.e., the leakage of the LLMs' training data. In general, we reveal many new insights in this paper for privacy protection of retrieval-augmented LLMs, which could benefit both LLMs and RAG systems builders.

The Good and The Bad: Exploring Privacy Issues in Retrieval-Augmented Generation (RAG)

Language agents that interact with the world on their own have great potential for automating digital tasks. While large language model (LLM) agents have made progress in understanding and executing tasks such as textual games and webpage control, many real-world tasks also require collaboration with humans or other LLMs in equal roles, which involves intent understanding, task coordination, and communication. To test LLM's ability to collaborate, we design a blocks-world environment, where two agents, each having unique goals and skills, build a target structure together. To complete the goals, they can act in the world and communicate in natural language. Under this environment, we design increasingly challenging settings to evaluate different collaboration perspectives, from independent to more complex, dependent tasks. We further adopt chain-of-thought prompts that include intermediate reasoning steps to model the partner's state and identify and correct execution errors. Both human-machine and machine-machine experiments show that LLM agents have strong grounding capacities, and our approach significantly improves the evaluation metric.

Your Co-Workers Matter: Evaluating Collaborative Capabilities of Language Models in Blocks World

With the development of LLMs, the security threats of LLMs are getting more and more attention. Numerous jailbreak attacks have been proposed to assess the security defense of LLMs. Current jailbreak attacks primarily utilize scenario camouflage techniques. However their explicitly mention of malicious intent will be easily recognized and defended by LLMs. In this paper, we propose an indirect jailbreak attack approach, Puzzler, which can bypass the LLM's defensive strategies and obtain malicious response by implicitly providing LLMs with some clues about the original malicious query. In addition, inspired by the wisdom of "When unable to attack, defend" from Sun Tzu's Art of War, we adopt a defensive stance to gather clues about the original malicious query through LLMs. The experimental results indicate that the Query Success Rate of the Puzzler is 14.0%-82.7% higher than baselines on the most prominent LLMs. Furthermore, when tested against the state-of-the-art jailbreak detection approaches, Puzzler proves to be more effective at evading detection compared to baselines.

Play Guessing Game with LLM: Indirect Jailbreak Attack with Implicit Clues

The development of large language models tailored for handling patients’ clinical notes is often hindered by the limited accessibility and usability of these notes due to strict privacy regulations.
To address these challenges, we first create synthetic large-scale clinical notes using publicly available case reports extracted from biomedical literature.
We then use these synthetic notes to train our specialized clinical large language model, Asclepius.
While Asclepius is trained on synthetic data, we assess its potential performance in real-world applications by evaluating it using real clinical notes.
We benchmark Asclepius against several other large language models, including GPT-3.5-turbo and other open-source alternatives. 
To further validate our approach using synthetic notes, we also compare Asclepius with its variants trained on real clinical notes. 
Our findings convincingly demonstrate that synthetic clinical notes can serve as viable substitutes for real ones when constructing high-performing clinical language models. 
This conclusion is supported by detailed evaluations conducted by both GPT-4 and medical professionals. 
All resources—including weights, codes, and data—used in the development of Asclepius will be made publicly accessible for future research.

Publicly Shareable Clinical Large Language Model Built on Synthetic Clinical Notes

Molecule-text modeling, which aims to facilitate molecule-relevant tasks with a textual interface and textual knowledge, is an emerging research direction. Beyond single molecules, studying reaction-text modeling holds promise for helping the synthesis of new materials and drugs. However, previous works mostly neglect reaction-text modeling: they primarily focus on modeling individual molecule-text pairs or learning chemical reactions without texts in context. Additionally, one key task of reaction-text modeling -- experimental procedure prediction -- is less explored due to the absence of an open-source dataset. The task is to predict step-by-step actions of conducting chemical experiments and is crucial to automating chemical synthesis. To resolve the challenges above, we propose a new pretraining method, ReactXT, for reaction-text modeling, and a new dataset, OpenExp, for experimental procedure prediction. Specifically, ReactXT features three types of input contexts to incrementally pretrain LMs. Each of the three input contexts corresponds to a pretraining task to improve the text-based understanding of either reactions or single molecules. ReactXT demonstrates consistent improvements in experimental procedure prediction and molecule captioning and offers competitive results in retrosynthesis. Our code is available at https://github.com/syr-cn/ReactXT.

ReactXT: Understanding Molecular “Reaction-ship” via Reaction-Contextualized Molecule-Text Pretraining

Reinforcement learning (RL) has been widely used in training large language models (LLMs) for preventing unexpected outputs, e.g., reducing harmfulness and errors. However, existing RL methods mainly adopt instance-level reward, which cannot provide fine-grained supervision for complex reasoning tasks. As a result, the RL training cannot be fully aware of the specific part or step that actually leads to the incorrectness in model response. To address it, we propose a new RL method named RLMEC that incorporates a generative model as the reward model, which is trained by the erroneous solution rewriting task under the minimum editing constraint, which can produce token-level supervision for RL training. Based 0on the generative reward model, we design the token-level RL objective for training and an imitation-based regularization for stabilizing RL process. And these two objectives focus on the revision of the key tokens for the erroneous solution, reducing the effect of other unimportant tokens. Experiment results on 8 tasks have demonstrated the effectiveness of our approach. Our code and data will be publicly released.

Improving Large Language Models via Fine-grained Reinforcement Learning with Minimum Editing Constraint

Summarization is an important application of large language models (LLMs). Most previous evaluation of summarization models has focused on their content selection, faithfulness, grammaticality and coherence. 
However, it is well known that LLMs can reproduce and reinforce harmful social biases. This raises the question: Do biases affect model outputs in a constrained setting like summarization?

To help answer this question, we first motivate and introduce a number of definitions for biased behaviours in summarization models, along with practical operationalizations. 
Since we find that biases inherent to input documents can confound bias analysis in summaries, we propose a method to generate input documents with carefully controlled demographic attributes. This allows us to study summarizer behavior in a controlled setting, while still working with realistic input documents.

We measure gender bias in English summaries generated by both purpose-built summarization models and general purpose chat models as a case study. We find content selection in single document summarization to be largely unaffected by gender bias, while hallucinations exhibit evidence of bias.

To demonstrate the generality of our approach, we additionally investigate racial bias, including intersectional settings.

Bias in News Summarization: Measures, Pitfalls and Corpora

Large language models (LLMs) have revolutionized zero-shot task performance, mitigating the need for task-specific annotations while enhancing task generalizability. Despite its advancements, current methods using trigger phrases such as "Let's think step by step" remain limited. This study introduces PRomPTed, an approach that optimizes the zero-shot prompts for individual task instances following an innovative manner of "LLMs in the loop".
Our comprehensive evaluation across 13 datasets and 10 task types based on GPT-4 reveals that PRomPTed significantly outperforms both the naive zero-shot approaches and a strong baseline (i.e., "Output Refinement") which refines the task output instead of the input prompt. Our experimental results also confirmed the generalization of this advantage to the relatively weaker GPT-3.5. Even more intriguingly, we found that leveraging GPT-3.5 to rewrite prompts for the stronger GPT-4 not only matches but occasionally exceeds the efficacy of using GPT-4 as the prompt rewriter. Our research thus presents a huge value in not only enhancing zero-shot LLM performance but also potentially enabling supervising LLMs with their weaker counterparts, a capability attracting much interest recently. Finally, our additional experiments confirm the generalization of the advantages to open-source LLMs such as Mistral 7B and Mixtral 8x7B.

Instances Need More Care: Rewriting Prompts for Instances with LLMs in the Loop Yields Better Zero-Shot Performance

In the realm of event prediction, temporal knowledge graph forecasting (TKGF) stands as a pivotal technique. Previous approaches face the challenges of not utilizing experience during testing and relying on a single short-term history, which limits adaptation to evolving data. In this paper, we introduce the Online Neural-Symbolic Event Prediction (ONSEP) framework, which innovates by integrating dynamic causal rule mining (DCRM) and dual history augmented generation (DHAG). DCRM dynamically constructs causal rules from real-time data, allowing for swift adaptation to new causal relationships. In parallel, DHAG merges short-term and long-term historical contexts, leveraging a bi-branch approach to enrich event prediction. Our framework demonstrates notable performance enhancements across diverse datasets, with significant Hit@k (k=1,3,10) improvements, showcasing its ability to augment large language models (LLMs) for event prediction without necessitating extensive retraining. The ONSEP framework not only advances the field of TKGF but also underscores the potential of neural-symbolic approaches in adapting to dynamic data environments.

Downloads

Next from ACL 2024

Are Female Carpenters like Blue Bananas? A Corpus Investigation of Occupation Gender Typicality

Similar lecture

Gla-AI4BioMed at RRG24: Visual Instruction-tuned Adaptation for Radiology Report Generation