Austria

The discovery of novel antibiotics is critical to address the growing antimicrobial resistance (AMR). However, pharmaceutical industries face high costs (over $1 billion), long timelines, and a high failure rate, worsened by the rediscovery of known compounds. We propose an LLM-based pipeline that acts as an alert system, detecting prior evidence of antibiotic activity to prevent costly rediscoveries. The system integrates literature on organisms and chemicals into a Knowledge Graph (KG), ensuring taxonomic resolution, synonym handling, and multi-level evidence classification. We tested the pipeline on a private list of 73 potential antibiotic-producing organisms, disclosing 12 negative hits for evaluation. The results highlight the effectiveness of the pipeline for evidence reviewing, reducing false negatives, and accelerating decision-making. The KG for negative hits as well as the user interface for interactive exploration are available at https://github.com/idiap/abroad-kg-store and https://github.com/idiap/abroad-demo-webapp.

ACL 2025

Accelerating Antibiotic Discovery with Large Language Models and Knowledge Graphs

antibiotics

large language model

knowledge graph

## Welcome to NAACL 2022!
The Annual Meeting of the North American Chapter of the Association for Computational Linguistics (NAACL) is taking place July 10-15, 2022 as a hybrid event, in Seattle, WA and online. We are happy to welcome all of you to conference! 
 
The main conference program features oral presentations, in-person and virtual posters and demo sessions, a plenary session for our best paper presentations and awards, keynote presentations, a plenary panel on the place of linguistics and symbolic structures in NLP, and an Industrial Track panel on Careers in NLP.
 
Posters (including Findings of NAACL 2022) and demos are grouped by areas for both the in-person and the virtual sessions. For the virtual component, the talks will be on Zoom and the posters and the demos will be in GatherTown. The Student Research Workshop and will have an oral session and a poster session.
 
The program also features 6 Tutorials and 26 Workshops.
 
 We wish you a wonderful conference!
 
[The NAACL 2022 Organizing Committee](https://2022.naacl.org/committees/organization/)

NAACL 2022

2022 Annual Conference of the North American Chapter of the Association for Computational Linguistics

poster

### Welcome to The 63rd Annual Meeting of the Association for Computational Linguistics (ACL 2025)

Message from the General Chair: 
*It is my great pleasure and honor to welcome you to the 63rd Annual Meeting of the Association for Computational Linguistics (ACL 2025), held in beautiful Vienna, Austria, from July 27 to August 1, 2025. ACL2025continues our field’s tradition of excellence in scholarship, innovation, and inclusivity, and I am deeply grateful to the many volunteers who have worked tirelessly to bring this event to life.* 
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Welcome to The 63rd Annual Meeting of the Association for Computational Linguistics (ACL 2025)

We investigate the utility of Large Language Models for automated taxonomy generation and completion specifically applied to taxonomies from the food technology industry. We explore the extent to which taxonomies can be completed from a seed taxonomy or generated without a seed from a set of known concepts, in an iterative fashion using recent prompting techniques.
Experiments on five taxonomies using an open-source LLM (Llama-3), while promising, point to the difficulty of correctly placing inner nodes.

FoodTaxo: Generating Food Taxonomies with Large Language Models

This paper presents a user-centered, empirically guided approach to multilingual metadata enrichment for children’s books. We combine LLMs with human-in-the-loop quality control in a scalable CI/CD pipeline to curate brand collections that enhance book discovery and engagement for young readers across multiple European markets. Our results demonstrate that this hybrid approach delivers high-quality, child-appropriate labels, improves user experience, and accelerates deployment in real-world production environments. This work offers practical insights for applying generative NLP in the media and publishing industry.

Enriching children’s stories with LLMs: Delivering multilingual data enrichment for children’s books at scale and across markets

Modern text processing pipelines demand robust methods to remove extraneous content while preserving a document's core message. Traditional approaches—such as HTML boilerplate extraction or keyword filters—often fail in multilingual settings and struggle with context-sensitive nuances, whereas Large Language Models (LLMs) offer improved quality at high computational cost. We introduce SORE (Semantic Outlier Removal), a cost-effective, transparent method that leverages multilingual sentence embeddings and approximate nearest-neighbor search to identify and excise unwanted text segments. By first identifying core content via metadata embedding and then flagging segments that either closely match predefined outlier groups or deviate significantly from the core, SORE achieves near-LLM extraction precision at a fraction of the cost. Experiments on HTML datasets demonstrate that SORE outperforms structural methods and yield high precision in diverse scenarios. Our system is currently deployed in production, processing millions of documents daily across multiple languages while maintaining both efficiency and accuracy. To facilitate reproducibility and further research, we will publicly release our implementation and evaluation datasets.

Semantic Outlier Removal with Embedding Models and LLMs

Named Entity Recognition (NER) for low-resource variants of English remains challenging, as most NER models are trained on datasets predominantly focused on American or British English. While recent work has shown that proprietary Large Language Models (LLMs) can perform NER effectively in low-resource settings through in-context learning, practical deployment is limited by their high computational costs and privacy concerns. Open-source Small Language Models (SLMs) offer promising alternatives, but the tendency of these Language Models (LM) to hallucinate poses challenges for production use. To address this, we introduce SLENDER, a novel output format for LM-based NER that achieves a three-fold reduction in inference time on average compared to JSON format, which is widely used for structured outputs. Our approach using Gemma-2-9B-it with the SLENDER output format and constrained decoding in zero-shot settings outperforms the en_core_web_trf model from SpaCy, an industry-standard NER tool, in all five regions of the Worldwide test set.

SLENDER: Structured Outputs for SLM-based NER in Low-Resource Englishes

Virtual Teaching Assistants (VTAs) powered by Large Language Models (LLMs) have the potential to enhance student learning by providing instant feedback and facilitating multi-turn interactions. However, empirical studies on their effectiveness and acceptance in real-world classrooms are limited, leaving their practical impact uncertain. In this study, we develop an LLM-based VTA and deploy it in an introductory AI programming course with 477 graduate students. To assess how student perceptions of the VTA’s performance evolve over time, we conduct three rounds of comprehensive surveys at different stages of the course. Additionally, we analyze 3,869 student–VTA interaction pairs to identify common question types and engagement patterns. We then compare these interactions with traditional student-human instructor interactions to evaluate the VTA’s role in the learning process. Through a large-scale empirical study and interaction analysis, we assess the feasibility of deploying VTAs in real-world classrooms and identify key challenges for broader adoption. Finally, we release the source code of our VTA system, fostering future advancements in AI-driven education.

A Large-Scale Real-World Evaluation of an LLM-Based Virtual Teaching Assistant

Effective content moderation is essential for video platforms to safeguard user experience and uphold community standards. While traditional video classification models effectively handle well-defined moderation tasks, they struggle with complicated scenarios such as implicit harmful content and contextual ambiguity. Multimodal large language models (MLLMs) offer a promising solution to these limitations with their superior cross-modal reasoning and contextual understanding. However, two key challenges hinder their industrial adoption. First, the high computational cost of MLLMs makes full-scale deployment impractical. Second, adapting generative models for discriminative classification remains an open research problem. In this paper, we first introduce an efficient method to transform a generative MLLM into a multimodal classifier using minimal discriminative training data. To enable industry-scale deployment, we then propose a router-ranking cascade system that integrates MLLMs with a lightweight router model. Offline experiments demonstrate that our MLLM-based approach improves F1 score by 66.50% over traditional classifiers while requiring only 2% of the fine-tuning data. Online evaluations show that our system increases automatic content moderation volume by 41%, while the cascading deployment reduces computational cost to only 1.5% of direct full-scale deployment.

Filter-And-Refine: A MLLM Based Cascade System for Industrial-Scale Video Content Moderation

Ambiguous user queries pose a significant challenge in task-oriented dialogue systems relying on information retrieval. While Large Language Models (LLMs) have shown promise in generating clarification questions to tackle query ambiguity, they rely solely on the top-k retrieved documents for clarification which fails when ambiguity is too high to retrieve relevant documents in the first place. Traditional approaches 
lack principled mechanisms to determine when to use broad domain knowledge vs specific retrieved document context for clarification. We propose AsK, a novel hybrid approach that dynamically chooses between document-based or aspect-based clarification based on query ambiguity. Our approach requires no labeled clarification data and introduces: (1) Weakly-supervised Longformer-based ambiguity analysis, (2) Automated domain-specific aspect generation using clustering and LLMs and (3) LLM-powered clarification generation. AsK demonstrates significant improvements over baselines in both single-turn and multi-turn settings (recall@5 gain of ~20%) when evaluated on product troubleshooting and product search datasets.

ASK: Aspects and Retrieval based Hybrid Clarification in Task Oriented Dialogue Systems

Electronic Health Records contain vast amounts of valuable clinical data, much of which is stored as unstructured text. Extracting meaningful clinical events (e.g., disorders, symptoms, findings, medications, and procedures etc.) in context within real-world healthcare settings is crucial for enabling downstream applications such as disease prediction, clinical coding for billing and decision support.
After Named Entity Recognition and Linking (NER+L) methodology, the identified concepts need to be further classified (i.e. contextualized) for distinct properties such as their relevance to the patient, their temporal and negated status for meaningful clinical use. 
We present a solution that, using an existing NER+L approach - MedCAT, classifies and contextualizes medical entities at scale. We evaluate the NLP approaches through 14 distinct real-world clinical text classification projects, testing our suite of models tailored to different clinical NLP needs. For tasks requiring high minority class recall, BERT proves the most effective when coupled with class imbalance mitigation techniques, outperforming Bi-LSTM with up to 28%. For majority class focused tasks, Bi-LSTM offers a lightweight alternative with, on average, 32% faster training time and lower computational cost. Importantly, these tools are integrated into an openly available library, enabling users to select the best model for their specific downstream applications.

A Framework for Flexible Extraction of Clinical Event Contextual Properties from Electronic Health Records

With the emergence of ChatGPT, Transformer models have significantly advanced text classification and related tasks. Decoder-only models such as Llama exhibit strong performance and flexibility, yet they suffer from inefficiency on inference due to token-by-token generation, and their effectiveness in text classification tasks heavily depends on prompt quality. Moreover, their substantial GPU resource requirements often limit widespread adoption. Thus, the question of whether smaller language models are capable of effectively handling text classification tasks emerges as a topic of significant interest. However, the selection of appropriate models and methodologies remains largely underexplored. In this paper, we conduct a comprehensive evaluation of prompt engineering and supervised fine-tuning methods for transformer-based text classification. Specifically, we focus on practical industrial scenarios, including email classification, legal document categorization, and the classification of extremely long academic texts. We examine the strengths and limitations of smaller models, with particular attention to both their performance and their efficiency in Video Random-Access Memory (VRAM) utilization, thereby providing valuable insights for the local deployment and application of compact models in industrial settings.

Small Language Models in the Real World: Insights from Industrial Text Classification

Text chunking is fundamental to modern retrieval-augmented systems, yet existing methods often struggle with maintaining semantic coherence, both within and across chunks, while dealing with document structure and noise. We present AutoChunker, a bottom-up approach for text chunking that combines document structure awareness with noise elimination. AutoChunker leverages language models to identify and segregate logical units of information (a chunk) while preserving document hierarchy through a tree-based representation. To evaluate the chunking operator, we introduce a comprehensive evaluation framework based on five core tenets: noise reduction, completeness, context coherence, task relevance, and retrieval performance. Experimental results on Support and Wikipedia articles demonstrate that AutoChunker significantly outperforms existing methods, reducing noise while improving chunk completeness compared to state-of-the-art baselines. When integrated with an online product support system, our approach led to improvements in retrieval performance and customer return rates. Our work not only advances the state of text chunking but also provides a standardized framework for evaluating chunking strategies, addressing a critical gap in the field.

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Next from ACL 2025

FoodTaxo: Generating Food Taxonomies with Large Language Models

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