China

While large, biomedical documents with complex terminology are in need of being understood more easily and efficiently, summarizing this kind of content can be problematic, as Large Language Models (LLMs) aren&#39;t always trustworthy. Considering the importance of comprehending Cardiovascular Diseases, we study in depth the ability of different state-of-the-art biomedical LLMs to generate factual and certain summaries in this topic, and examine which generation choices can influence their trustworthiness. To that end, besides using factuality metrics, we employ techniques for token-level uncertainty estimation, an area that has received little attention from the scientific community. Our results reveal dissimilarities between LLMs and generation methods, and highlight connections between factuality and uncertainty metrics, thereby laying the groundwork for further investigation in the area.

EMNLP 2025

Towards Trustworthy Summarization of Cardiovascular Articles: A Factuality-and-Uncertainty-Aware Biomedical LLM Approach

biomedical llms

biomedical summarization

cardiovascular diseases

trustworthiness

### Welcome to ACL 2023, the 61st Annual Meeting of the Association for Computational Linguistics! 
 The conference will be held in Toronto, Canada, July 9-14, 2023. 
Following the succession of the recent conferences in our field, ACL 2023 will adopt a hybrid format.
While the impact of Covid has considerably diminished in terms of traveling, obtaining visas to Canada
entails a very long process. Moreover, the global economic conditions pose challenges for many individuals to travel to conferences. Recognizing these circumstances, we know many participants may not be
able to attend the conference in person. Therefore, we are committed to providing a great virtual platform
so everyone has the opportunity to interact with other participants and enjoy the conference. Based on the
current registered participants, approxiately 30% have chosen to attend the conference virtually. Whether
you join us in person or virtually, we sincerely hope everyone has a remarkable conference experience. 
This General Chair’s message is where I express my gratitude to the many individuals who have made
enormous contributions to the conference over the past year.

Read [**ACL 2023 General Chair's message**](https://docs.google.com/document/d/1WobYM7norbG4dI48s75HfJoD89qgX5a_F-6U8AteLSA/edit?usp=sharing/) in full.

##### **[Conference Handbook](https://2023.aclweb.org/downloads/acl2023-handbook.pdf)**

ACL 2023

The Association for Computational Linguistics (ACL) is the premier international scientific and professional society for people working on computational problems involving human language, a field often referred to as either computational linguistics or natural language processing.

While large, biomedical documents with complex terminology are in need of being understood more easily and efficiently, summarizing this kind of content can be problematic, as Large Language Models (LLMs) aren't always trustworthy. Considering the importance of comprehending Cardiovascular Diseases, we study in depth the ability of different state-of-the-art biomedical LLMs to generate factual and certain summaries in this topic, and examine which generation choices can influence their trustworthiness. To that end, besides using factuality metrics, we employ techniques for token-level uncertainty estimation, an area that has received little attention from the scientific community. Our results reveal dissimilarities between LLMs and generation methods, and highlight connections between factuality and uncertainty metrics, thereby laying the groundwork for further investigation in the area.

workshop paper

## Welcome!
"I am excited to welcome you to this year’s edition of the Conference on Empirical Methods in Natural Language Processing! Importantly, it marks the 30th edition of EMNLP. With over 8,000 submissions, more than 3,000 accepted papers, and thousands of attendees, we have come a long way from that first
workshop, which had 14 accepted papers. As the field looks ahead, Suzhou is the fitting location for celebrating this milestone: rooted in a long literary tradition, yet modern and forward-looking, and home to a large share of the NLP community." 

*Message from the General Chair, Dirk Hovy*

Celebrate 30 Years of EMNLP! 
EMNLP 2025 will be held in Suzhou, China from November 5th to November 9th, 2025.

Recent papers show LLMs achieve near-random accuracy in causal relation classification, raising questions about whether such failures arise from limited pretraining exposure or deeper representational gaps. We investigate this under uncertainty-based evaluation, testing whether pretraining exposure to causal examples improves causal understanding using >18K PubMed sentences—half from The Pile corpus, half post-2024—across seven models (Pythia-1.4B/7B/12B, GPT-J-6B, Dolly-7B/12B, Qwen-7B). We analyze model behavior through: (i) causal classification, where the model identifies causal relationships in text, and (ii) verbatim memorization probing, where we assess whether the model prefers previously seen causal statements over their paraphrases. Models perform four-way classification (direct/conditional/correlational/no-relationship) and select between originals and their generated paraphrases. Results show 
almost identical accuracy on seen/unseen sentences (p>0.05), no memorization bias (24.8\% original selection), output distribution over the possible options almost flat --- with entropic values near the maximum (1.35/1.39), confirming random guessing. Instruction-tuned models show severe miscalibration (Qwen: >95\% confidence, 32.8\% accuracy, ECE=0.49). Conditional relations induce highest entropy (+11\% vs direct). These findings suggest that failures in causal understanding arise from the lack of structured causal representation, rather than insufficient exposure to causal examples during pretraining.

Causal Understanding by LLMs: The Role of Uncertainty

Ambiguous words or underspecified references require interlocutors to resolve them, often by relying on shared context and commonsense knowledge. Therefore, we systematically investigate whether Large Language Models (LLMs) can leverage commonsense to resolve referential ambiguity in multi-turn conversations and analyze their behavior when ambiguity persists. Further, we study how requests for simplified language affect this capacity. Using a novel multilingual evaluation dataset, we test DeepSeek v3, GPT-4o, Qwen3-32B, GPT-4o-mini, and Llama-3.1-8B via LLM-as-Judge and human annotations. Our findings indicate that current LLMs struggle to resolve ambiguity effectively: they tend to commit to a single interpretation or cover all possible references, rather than hedging or seeking clarification. This limitation becomes more pronounced under simplification prompts, which drastically reduce the use of commonsense reasoning and diverse response strategies. Fine-tuning Llama-3.1-8B with Direct Preference Optimization substantially improves ambiguity resolution across all request types. These results underscore the need for advanced fine-tuning to improve LLMs' handling of ambiguity and to ensure robust performance across diverse communication styles.

It Depends: Resolving Referential Ambiguity in Minimal Contexts with Commonsense Knowledge

We study the source of uncertainty in DeepSeek R1-32B by analyzing its self-reported verbal confidence on question answering (QA) tasks. In the default answer-then-confidence setting, the model is regularly over-confident, whereas semantic entropy - obtained by sampling many responses - remains reliable. We hypothesize that this is because of semantic entropy's larger test-time compute, which lets us explore the model's predictive distribution. We show that granting DeepSeek the budget to explore its distribution by forcing a long chain-of-thought before the final answer greatly improves its verbal score effectiveness, even on simple fact-retrieval questions that normally require no reasoning. Our analysis concludes that reliable uncertainty estimation requires explicit exploration of the generative space, and self-reported confidence is trustworthy only after such exploration.

Read Your Own Mind: Reasoning Helps Surface Self-Confidence Signals in LLMs

In recent years, we have seen an increased usage of neural ranking models in the information retrieval domain. Although language model-based rankers have shown significant progress in performing ranking tasks, little to no work has addressed the issue of fine-tuning them in the presence of label noise in the training data. In a general learning setting, training models in the presence of noisy labeled data is studied extensively. To this end, confidence calibration approaches have shown significant promise; however, their usage in training neural ranking models is relatively less studied. In this work, we address this gap by adapting and analyzing regularization-based calibration approaches to reduce the effect of label noise in ranking tasks. Specifically, we study label relaxation in neural ranking models. We demonstrate the effectiveness of this approach by performing extensive evaluations comparing the label relaxation approach to standard loss functions. Additionally, we analyze the calibration error associated with the loss functions.
After evaluating on five different noise levels, two different ranking models, and four diverse ranking datasets, the results suggest that label relaxation can improve the performance of the ranking models under noisy labels. Furthermore, we find that label relaxation reduces calibration error, although it suggests a better metric to be used for neural ranking models.

Calibrating Language Models for Neural Ranking under Noisy Supervision with Relaxed Labels

Large Language Models (LLMs) suffer significant performance degradation in multi-turn conversations when information is presented incrementally. Given that multi-turn conversations characterize everyday interactions with LLMs, this degradation poses a severe challenge to real world usability. We hypothesize that abrupt increases in model uncertainty signal misalignment in multi-turn LLM interactions, and we exploit this insight to dynamically realign conversational context. We introduce ERGO (Entropy-guided Resetting for Generation Optimization), which continuously quantifies internal uncertainty via Shannon entropy over next token distributions and triggers adaptive prompt consolidation when a sharp spike in entropy is detected. By treating uncertainty as a first class signal rather than a nuisance to eliminate, ERGO embraces variability in language and modeling, representing and responding to uncertainty. In multi‐turn tasks with incrementally revealed instructions, ERGO yields a 56.6% average performance gain over standard baselines, increases aptitude (peak performance capability) by 24.7%, and decreases unreliability (variability in performance) by 35.3%, demonstrating that uncertainty aware interventions can improve both accuracy and reliability in conversational AI.

ERGO: Entropy-guided Resetting for Generation Optimization in Multi-turn Language Models

Natural language processing (NLP) for low-resource languages remains fundamentally constrained by the lack of textual corpora, standardized orthographies, and scalable annotation pipelines. While recent advances in large language models have improved cross-lingual transfer, they remain inaccessible to underrepresented communities due to their reliance on massive, pre-collected data and centralized infrastructure. In this position paper, we argue for a paradigm shift toward open-ended, interactive language discovery, where AI systems learn new languages dynamically through dialogue rather than static datasets. We contend that the future of language technology, particularly for low-resource and under-documented languages, must move beyond static data collection pipelines toward interactive, uncertainty-driven discovery, where learning emerges dynamically from human-machine collaboration instead of being limited to pre-existing datasets. We propose a framework grounded in joint human-machine uncertainty, combining epistemic uncertainty from the model with hesitation cues and confidence signals from human speakers to guide interaction, query selection, and memory retention. This paper is a call to action: we advocate a rethinking of how AI engages with human knowledge in under-documented languages, moving from extractive data collection toward participatory, co-adaptive learning processes that respect and empower communities while discovering and preserving the world's linguistic diversity. This vision aligns with principles of human-centered AI and participatory design, emphasizing interactive, cooperative model building between AI systems and speakers.

Towards Open-Ended Discovery for Low-Resource NLP

This study investigates whether vision-language models (VLMs) can perform pragmatic inference, focusing on ignorance implicatures, utterances that imply the speaker's lack of precise knowledge. To test this, we systematically manipulated contextual cues: the visually depicted situation (visual cue) and QUD-based linguistic prompts (linguistic cue). When only visual cues were provided, three state-of-the-art VLMs (GPT-4o, Gemini 1.5 Pro, and Claude 3.5 sonnet) produced interpretations largely based on the lexical meaning of the modified numerals. When linguistic cues were added to enhance contextual informativeness, Claude exhibited more human-like inference by integrating both types of contextual cues. In contrast, GPT and Gemini favored precise, literal interpretations. Although the influence of contextual cues increased, they treated each contextual cue independently and aligned them with semantic features rather than engaging in context-driven reasoning. These findings suggest that although the models differ in how they handle contextual cues, Claude's ability to combine multiple cues may signal emerging pragmatic competence in multimodal models.

Can Vision-Language Models Infer Speaker's Ignorance? The Role of Visual and Linguistic Cues

Large Language Models (LLMs) are increasingly being used in real-world applications. However, concerns about the reliability of the content they generate persist, as it frequently deviates from factual correctness or exhibits deficiencies in logical reasoning. This paper proposes a novel decoding strategy aimed at enhancing both factual accuracy and inferential reasoning without requiring any modifications to the architecture or pre-trained parameters of LLMs. Our approach adjusts next-token probabilities by analyzing the trajectory of logits from lower to higher layers in Transformers and applying linear regression. We find that this **De**coding by **L**ogit **T**r**a**jectory-based approach (DeLTa) effectively reinforces factuality and reasoning while mitigating incorrect generation. Experiments on TruthfulQA demonstrate that DeLTa attains up to a 4.9% improvement over the baseline. Furthermore, it enhances performance by up to 8.1% on StrategyQA and 7.3% on GSM8K, both of which demand strong reasoning capabilities.

DeLTa: A Decoding Strategy based on Logit Trajectory Prediction Improves Factuality and Reasoning Ability

Large language models (LLMs) have demonstrated strong capabilities in text understanding and generation. However, they often lack factuality, producing a mixture of true and false information, especially in long-form generation. In this work, we investigates the factuality of long-form text generation across various large language models (LLMs), including GPT-4, Gemini-1.5-Pro, Claude-3-Opus, Llama-3-70B, and Mistral. Our analysis reveals that factuality tend to decline in later sentences of the generated text, accompanied by a rise in the number of unsupported claims. Furthermore, we explore the effectiveness of different evaluation settings to assess whether LLMs can accurately judge the correctness of their own outputs: Self-Known (the percentage of supported atomic claims, decomposed from LLM outputs, that the corresponding LLMs judge as correct) and Self-Unknown (the percentage of unsupported atomic claims that the corresponding LLMs judge as incorrect). The results indicate that even advanced models fail to achieve perfect Self-Known scores, while their Self-Unknown scores remain notably above zero, reflecting ongoing uncertainty in their self-assessments. Moreover, we find a correlation between higher Self-Known scores and improved factuality, while higher Self-Unknown scores are associated with lower factuality. Even without significant changes in the models’ self-judgment (Self-Known and Self-Unknown), the number of unsupported claims can increases, likely as an artifact of long-form generation. Additional Retrieval-Augmented Generation (RAG) experiments also show the limitations of current LLMs in long-form generation, and provide the more research is needed to improve factuality in long-form text generation.

Investigating Factuality in Long-Form Text Generation: The Roles of Self-Known and Self-Unknown

This paper examines the potential of combining gamification and speech technology to support early reading development in children. We introduce Wordcaster, a game where players cast spells by pronouncing words aloud, using real-time automatic speech recognition (ASR) to provide feedback and encourage participation. A pilot study was conducted with three bilingual children—native Arabic speakers learning English—using a fixed list of 20 English words. Results showed increased ASR accuracy between sessions, and all children reported high enjoyment. These findings support a direction for scalable, speech-driven reading support.

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