The role of the hippocampus in representing space is widely supported. Neurons that increase their firing rate when an animal occupies a certain region, 'Place Cells,' have been thoroughly identified and studied in multiple species. This unique population of neurons has been thought to support a cognitive-map like representation of space in the brain; however, little is known about how these representations are formed in the common marmoset during free navigation in a 3D environment. Moreover, whether these representations are modulated by spatial view or movement kinematic has yet to be determined. In this work, we sought to identify the firing properties of neurons in the CA fields of the hippocampus while we register spatial and view information of freely navigating marmosets as they engage in a variety of foraging behaviors in 3D space. For this purpose, we habituated the experimental subjects to freely move inside a plexiglass recording chamber with four vertical levels while wearing affixed infrared reflective markers on top of skull implants that allowed for 6 degrees of freedom position and head direction camera tracking (Optitrack, Natural Point Inc, USA). Using MRI-guided neuro-navigation techniques, we chronically implanted 32ch microwire arrays in the hippocampus, and we were able to record single-unit activity during the aforementioned behaviors wirelessly. We analyzed data from 2 animals; spatial view and occupancy rate maps were constructed using 20cm3 bins. Spatial Information Content (SIC) was calculated independently for place and view for 200 total cells. SIC was higher for the spatial view than body position. We also found cells whose firing rate was highly correlated for both body velocity and head angular velocity.

Representation of 3D space in the hippocampus of freely moving marmosets

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PS-2-F -  Cognition and Behavior

poster

Colleagues and Friends:

I am very happy to welcome you to the 14th annual Canadian Neuroscience Meeting, and to the first virtual edition of our meeting. I want to highlight the important work the CAN meeting chair, **Roger Thompson** and co-chair, **Alyson Fournier**, did to put together the great program we are offering this year. Moving to a virtual format required a complete re-design of the program, and both Roger and Alyson did a splendid job in providing us with an appealing and well adapted program for our first virtual event. I wish to thank them for this very important effort.

Highlights of this year’s scientific meeting include invited speakers **Michael Hausser, Franck Polleux, Gwyneth Card, Magdalena Götz**and Brain Prize winner **Huda Zoghbi**. Plenary and parallel symposia, proposed by our members complete our diverse [scientific program.](https://can-acn.org/meeting-2021/program-2021/)

The 2021 Advocacy session, chaired and organized by CAN advocacy committee chair **Karun Singh**, will feature a special lecture and question period with Member of Parliament and past Science Minister **Kirsty Duncan**. This will be followed by a short overview of CAN’s advocacy activities over the last year. We invite you to participate in this session for insight from Dr. Duncan on the workings of Parliament Hill, and to learn more about what CAN has been doing to promote neuroscience research in Canada.

We are also excited to host **Lisa Willis** in the Equity Diversity and Inclusion session, organized by EDI committee chair **Jibran Khokhar**.

A special highlight of our meeting will be the lectures by award-winning young neuroscientists. We are please to host the CAN 2020 Young Investigator Award winner **Mihaela Iordanova**, and CAN 2021 Young Investigator Award winners **Aaron Phillips** and **Tabrez Siddiqui**. Highlights will also include presentation by the top three winners of the CAN-CIHR-INMHA Brain Star Award winners, **Claire Gizowski, Nuria Daviu Abant** and **Lukas Tamayo-Orrego**.

Independently organized satellite symposia complement and complete this exciting program, check them out here: https://can-acn.org/meeting-2021/2021-satellite-symposia/

Some of the most engaging sessions are always the poster sessions featuring the work of our trainees, so make sure to log in to Gather Town during the poster sessions to chat with the presenters.
We hope you enjoy this program, and look forward to welcoming you, virtually.

Shernaz Bamji

President of the Canadian Association for Neuroscience

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DIEGO B. PIZA

1

SHORT BIO

Presentations

Representation of 3D space in the hippocampus of freely moving marmosets